In the tradition of UNDERWORLD and DISTRICT 9, all of Manhattan is quarantined when the Lupine virus spreads like wildfire, turning innocent civilians into ravenous wolves. Nothing short of a nuclear blast can stop the monstrous virus.

父母双双遇害，而犯人又被无罪释放，这一切都让青年杰森·帕福德（凯勒·威利特 Kyler Willett 饰）远离曾经给予了误伤信仰的教堂，转而化身为周游声色犬马之间的浪荡子。某天，原教堂的迪克曼神父（莱斯特·霍尔莫斯Lassiter Holmes 饰）找到杰森，此前神父的搭档康纳利神父（丹尼·特乔 Danny Trejo 饰）在一次驱魔仪式中惨遭杀害，而恶魔的力量正不断强大，世界面临被黑暗统治的危险。为了对抗即将到来的危机，迪克曼神父希望杰森能回归教堂，成为自己的得力助手。半信半疑的杰森回到教堂，并且得知专事与魔鬼抗争的神秘组织驱魔圣教（Cloth）的存在。 　　在此之后，他将拿起各种强大的武器，与伙伴们并肩战斗……

While returning from a military expedition a helicopter crash lands a commando unit in a dense, remote tropical jungle – a lost world populated by dinosaurs. Now they must find a way out of this isolated valley before becoming prey for prehistoric predators.